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PMEL17/SILV Mouse, Clone: SPM286, Novus Biologicals™
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Catalog No. NBP232855F Shop All R&D Systems Products
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NBP232855F 0.02 mg
NBP232855A 0.1 mg
NBP232855B 0.2 mg
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Catalog No. NBP232855F Supplier Novus Biologicals Supplier No. NBP2328550.02MG
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Description

Mouse Monoclonal Antibody

PMEL17/SILV Monoclonal specifically detects PMEL17/SILV in Human, Equine, Rat (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen PMEL17/SILV
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone SPM286
Conjugate Unconjugated
Dilution Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P40967
Gene Alias D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17
Gene Symbols PMEL
Host Species Mouse
Immunogen Membranes from a human melanoma metastasis
Purification Method Protein A purified
Quantity 0.02 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6490
Test Specificity By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Target Species Human, Equine, Rat (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG2b κ
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