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PNU 120596, Tocris Bioscience™

Positive allosteric modulator of α7 nAChR; active in vivo

Manufacturer:  Tocris Bioscience 2498/5

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Catalog No. 24-985


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Description

Description

Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (EC 50 = 216 nM), with no detectable effect on α4β2, α3β4 and α9α10 receptors. Active in vivo following systemic administration. Neuroprotective in an in vivo model of transient focal cerebral ischemia.
Specifications

Specifications

N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea
>99%
Observed MW: 311.72
501925-31-1
C13H14ClN3O4
5mg
Safety and Handling

Safety and Handling

Recommended Storage : Desiccate at 4°C

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