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PNU 120596

Name: PNU 120596
Brand: R&D Systems
SKU: 24-985
Price: 147.32 USD

Positive allosteric modulator of α7 nAChRs; active in vivo

Supplier: R&D Systems 2498/5

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Catalog No. 24-985

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Description

PNU 120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (EC50 = 216 nM), with no detectable effect on α4β2, α3β4 and α9α10 receptors. Active in vivo following systemic administration. Neuroprotective in an in vivo model of transient focal cerebral ischemia.

Specifications

Chemical Name or Material	N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea
Assay Percent Range	>99%
Molecular Formula	C₁₃H₁₄ClN₃O₄

CAS	501925-31-1
Quantity	5 mg
Formula Weight	Observed MW: 311.72

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Recommended Storage : Desiccate at +4°C

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PNU 120596

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