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Podocalyxin Like Antibody (3D3), DyLight 650, Novus Biologicals™
SDP

Catalog No. NBP233108C Shop All R&D Systems Products
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NBP233108C 0.1 mL
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Catalog No. NBP233108C Supplier Novus Biologicals Supplier No. NBP233108C
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Description

Mouse Monoclonal Antibody

Podocalyxin Like Monoclonal specifically detects Podocalyxin Like in Human, Mouse, Rat, Rabbit samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular).

Specifications

Antigen Podocalyxin Like
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone 3D3
Conjugate DyLight 650
Dilution Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1
Gene Symbols PODXL
Host Species Mouse
Immunogen A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human Podocalyxin Like (Uniprot: O00592)
Purification Method Affinity Purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cellular Markers, Embryonic Stem Cell Markers, Hematopoietic Stem Cell Markers, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 5420
Test Specificity Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Target Species Human, Mouse, Rat, Rabbit
Content And Storage Store at 4C in the dark.
Isotype IgG1 κ
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For Research Use Only

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