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Podocalyxin Like Antibody (3D3), Novus Biologicals™
SDP

Catalog No. NBP225219 Shop All R&D Systems Products
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NBP225219 0.1 mg
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Catalog No. NBP225219 Supplier Novus Biologicals Supplier No. NBP225219
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Mouse Monoclonal Antibody has been used in 6 publications

Podocalyxin Like Monoclonal specifically detects Podocalyxin Like in Human, Mouse, Rat, Rabbit samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular).

Specifications

Antigen Podocalyxin Like
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 3D3
Concentration 0.2 mg/ml
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, Flow (Intracellular)
Gene Accession No. NP_001018121
Gene Alias Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1
Gene Symbols PODXL
Host Species Mouse
Immunogen A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human Podocalyxin Like (Uniprot: O00592)
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cellular Markers, Embryonic Stem Cell Markers, Hematopoietic Stem Cell Markers, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 5420
Test Specificity Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Target Species Human, Mouse, Rat, Rabbit
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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