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Podocalyxin Like Antibody (PODXL/2185), Alexa Fluor™ 488, Novus Biologicals™
SDP

Catalog No. NB011782 Shop All R&D Systems Products
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NB011782 0.1 mL
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Catalog No. NB011782 Supplier Novus Biologicals Supplier No. NBP279884AF488
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Mouse Monoclonal Antibody

Podocalyxin Like Monoclonal specifically detects Podocalyxin Like in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Podocalyxin Like
Applications Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone PODXL/2185
Conjugate Alexa Fluor 488
Dilution Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1
Gene Symbols PODXL
Host Species Mouse
Immunogen Recombinant fragment of human Podocalyxin Like (around aa 310-447) (exact sequence is proprietary) (Uniprot: O00592)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Stem Cell Markers
Primary or Secondary Primary
Test Specificity Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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