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Pol Iota Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7140776
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50-156-0034 20 μL
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Catalog No. 50-156-0034 Supplier Bethyl Laboratories, Inc Supplier No. A301304AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5′-deoxyribose phosphate at abasic sites, but may not have lyase activity.

Specifications

Antigen Pol Iota
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene POLI
Gene Accession No. Q9UNA4
Gene Alias RAD30B, RAD3OB
Gene Symbols POLI
Host Species Rabbit
Immunogen Between 690 and 715
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11201
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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