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PPP6C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen PPP6C
Concentration 0.13 mg/mL
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-0529
SDP
Encompass_Preferred
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Proteintech Group Inc
158521AP150UL
150 μL
Each of 1 for $518.60
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Description

Description

Distinct DNA repair pathways minimize the consequences of mutagenic events. Reactive oxygen species (ROS) are highly reactive atoms with an unpaired electron that are conducive to double-strand DNA breaking events. Artemis, named after the Greek goddess for the protection of children, is one of the major proteins contributing to the preservation of double-strand breaks in DNA by cutting away the damaged parts of the DNA, which allows the strands to rejoin. Artemis is a single-strand-specific 5′ to 3′ exonuclease that forms a complex with the 469 kDa DNA-dependent protein kinase (DNA-PKcs). DNA-PKcs phosphorylates Artemis, and Artemis acquires endonucleolytic activity on 5′ and 3′ overhangs and hairpins. These activities are essential for V(D)J recombination and for the 5′ and 3′ overhang processing in nonhomologous DNA end joining.
Specifications

Specifications

PPP6C
Immunoprecipitation, Western Blot
Unconjugated
Rabbit
Human, Mouse, Rat
O00743, Q64620, Q9CQR6
171121, 5537, 67857
PPP6C Fusion Protein Ag8670
Primary
-20°C
PPP6C
0.13 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
PP6C, PPP6, PPP6C
Ppp6c
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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Documents

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