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Progesterone R/NR3C3 Antibody (PR484), DyLight 550, Novus Biologicals™
SDP

Catalog No. NBP233325R Shop All R&D Systems Products
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Description

Mouse Monoclonal Antibody

Progesterone R/NR3C3 Monoclonal specifically detects Progesterone R/NR3C3 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Progesterone R/NR3C3
Applications Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone PR484
Conjugate DyLight 550
Dilution Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
Gene Symbols PGR
Host Species Mouse
Immunogen Recombinant full-length human Progesterone R/NR3C3 protein (PGR) (Uniprot: P06401 )
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Breast Cancer, Cancer
Primary or Secondary Primary
Gene ID (Entrez) 5241
Test Specificity This monoclonal antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Target Species Human
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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