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Invitrogen™ PRR7 Monoclonal Antibody (TRAP3/10)
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Catalog No. PIMA110448
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100 μg
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Catalog No. Quantity
PIMA110448 100 μg
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Catalog No. PIMA110448 Supplier Invitrogen™ Supplier No. MA110448
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Description

Mouse Monoclonal Antibody

This antibody recognizes an epitope located in the C-terminal part of the intracellular domain of PRR7/TRAP3 (amino acids 126-253 of human PRR7 / TRAP3), a 28 kDa proline-rich membrane protein presumably associated with NMDA receptor complex. Immunocytochemistry: Cell culture fixed with 4% paraformaldehyde, permeabilized with 0.1% Triton-X100.

PRR7/TRAP3 (proline-rich 7, transmembrane adaptor protein 3) is a 28 kDa transmembrane adaptor protein ubiquitously expressed at low level (most in brain). Its amino acid sequence is extremely conserved among mammalian and other species. PRR7/TRAP3 contains potential palmitoylation motif and is found in lipid rafts. It is a part of the complex postsynaptic density fraction in neurons and associates with PSD-95, NMDA receptor and probably other proteins. The intracellular domain of PRR7/TRAP3 contains several tyrosines, a proline-rich sequence, and a C-terminal PDZ-binding motif. So far nothing is known about function of this protein. It may be involved in regulation of some receptor signaling and in formation of neurologic and immunologic synapse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRR7
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone TRAP3/10
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene PRR7
Gene Accession No. P0C6T3, Q3V0I2, Q8TB68
Gene Alias MGC10772; proline rich 7 (synaptic); proline rich 7, synaptic; proline-rich protein 7; Prr7; Synaptic proline-rich membrane protein; XM_484263
Gene Symbols PRR7
Host Species Mouse
Immunogen Recombinant C-terminal half of the intracellular domain of human PRR7/TRAP3 (amino acids 126-253).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 432763, 498704, 80758
Target Species Human, Mouse, Rat
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG2a
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