PSF/SFPQ Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-157-1864	Bethyl Laboratories, Inc IHC00304T	10 μL
50-157-1863	Bethyl Laboratories, Inc IHC00304	100 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, X. tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Panda,

SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression. SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program. Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer′s disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD. SFPQ protein may appears as 47 kDa, 52 kDa or 100 kDa molecules in various cell types.

Specifications

• Antigen: PSF/SFPQ
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: POMP100, PSF
• Immunogen: Between 657 and 707
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: SFPQ

• Applications: Immunofluorescence, Immunohistochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P23246, Q8VIJ6
• Gene ID (Entrez): 6421, 71514
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody