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PTH Mouse anti-Human, Clone-3H9, Novus Biologicals™
SDP

Catalog No. NB254320200 Shop All R&D Systems Products
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Catalog No. Quantity
NB254320200 200 μg
NB254320100 100 μg
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Catalog No. NB254320200 Supplier Novus Biologicals Supplier No. NBP254320200UG

Description

Mouse Monoclonal Antibody

IHC-P:Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer pH 6.0 for 10-20 min followed by cooling at RT for 20 minutes

Specifications

Antigen PTH
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Classification Monoclonal
Clone 3H9
Concentration 1 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1
Gene Symbols PTH
Host Species Mouse
Immunogen Synthetic peptide corresponding to amino acids 1 to 34 of mature PTH conjugated to a carrier
Molecular Weight of Antigen 9 kDa
Purification Method Protein A or G purified
Quantity 200 μg
Regulatory Status RUO
Research Discipline Apoptosis, Biologically Active Proteins, Cancer
Primary or Secondary Primary
Gene ID (Entrez) 5741
Test Specificity Epitope of this MAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Target Species Human
Content And Storage Store at -20 to -80C. Avoid freeze-thaw cycles.
Isotype IgG2b κ
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