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Invitrogen™ PUF60 Monoclonal Antibody (GT677)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527822

Catalog No. PIMA527822


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Description

Description

Positive Control: mouse brain, rat brain, 293T, A431, HeLa, HepG2 Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PUF60 encodes a protein that is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PUF60
Monoclonal
1.0 mg/mL
PBS with no preservative
Q3UEB3, Q9UHX1, Q9WV25
Puf60
Human PUF60.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG2a
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
GT677
Unconjugated
Puf60
2410104I19Rik; 2810454F19Rik; 60 kDa poly(U)-binding-splicing factor; FBP interacting repressor; FBP-interacting repressor; FIR; FLJ31379; FUSE-binding protein-interacting repressor; LOW QUALITY PROTEIN: poly(U)-binding-splicing factor PUF60; poly(U) binding splicing factor 60; poly(U) binding splicing factor 60KDa; poly(U)-binding-splicing factor PUF60; poly-U binding splicing factor 60; poly-U binding splicing factor 60K; poly-U binding splicing factor 60KDa; PUF60; pyrimidine tract binding splicing factor; RNA-binding protein Siah-BP; Ro ribonucleoprotein-binding protein 1; Ro-binding protein 1; RoBP1; ROBPI; Siah binding protein 1; siah binding protein 1; FBP interacting repressor; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1; siah-binding protein 1; SIAHBP1; Siah-BP1; similar to fuse-binding protein-interacting repressor isoform a; VRJS
Mouse
Protein G
RUO
22827, 67959, 84401
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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