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Tocris Bioscience™ PX 12
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Quantity:
10 mg
50 mg
Description
Thioredoxin-1 (Trx-1) inhibitor; irreversibly inactivates Trx-1 as a substrate for reduction by thioredoxin reductase (TR); competitively inhibits the reduction of Trx-1 by TR (Ki = 30.8 μM). Attenuates expression of HIF-1α, VEGF and iNOS (IC50 values are 7.2, 10.4 and 18.1 μM respectively). Exhibits antitumor activity; directly inhibits tubulin in vitro and decreases tumor microvessel density in vivo.
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Specifications
Specifications
| Quantity | 50 mg |
| Formula Weight | 188.31 |
| Purity | >99% |
| Molecular Weight (g/mol) | 188.31 |
| Chemical Name or Material | PX 12 |
Safety and Handling
| Recommended Storage | Store at +4°C |
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