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PXR Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
$150.00 - $590.00
Specifications
| Antigen | PXR |
|---|---|
| Concentration | Lot-Specific |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-2728
|
Active Motif
39590 |
10 μL |
Each for $150.00
|
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50-199-2727
|
Active Motif
39589 |
200 μL |
Each for $590.00
|
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Description
This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.Specifications
| PXR | |
| Western Blot | |
| Unconjugated | |
| Rabbit | |
| Human | |
| O75469 | |
| 8856 | |
| This PXR antibody was raised against a peptide containing amino acid residues 57-71 of human PXR. | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| NR1I2 |
| Lot-Specific | |
| Polyclonal | |
| Liquid | |
| RUO | |
| 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8 | |
| BXR; mPXR; NR1I2; Nuclear receptor subfamily 1 group I member 2; nuclear receptor subfamily 1, group 1, member 2; nuclear receptor subfamily 1, group I, member 2; ONR 1; ONR1; Orphan nuclear receptor PAR1; Orphan nuclear receptor PXR; PAR; PAR 1; PAR 2; PAR q; PAR1; PAR2; PARq; pregnane X nuclear receptor variant 2; Pregnane X receptor; pregnane X receptor (nuclear receptor sub family 1, group I, member 2); PRR; Pxr; PXR.1; PXR.2; PXR1; SAR; Steroid and xenobiotic receptor; SXR | |
| NR1I2 | |
| IgG | |
| Antigen affinity chromatography | |
| Antibody |
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