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Invitrogen™ PYY Polyclonal Antibody
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Catalog No. 01674458
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100 μL
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Catalog No. Quantity
01-674-458 100 μL
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Catalog No. 01-674-458 Supplier Invitrogen™ Supplier No. PA19582
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Description

Chicken Polyclonal Antibody

PA1-9582 detects PYY in human, mouse and rat samples. PA1-9582 has been successfully used in ELISA procedures. PA1-9582 immunogen is a synthetic peptide corresponding to amino acids 3-18 of human PYY (IKPEAPGEDASPEELN).

Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PYY
Applications ELISA
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Pyy
Gene Accession No. P10082, P10631, Q9EPS2
Gene Alias GHYY; Peptide tyrosine tyrosine; peptide tyrosine-tyrosine (YY); peptide YY; peptide YY (mapped); Peptide YY(3-36); Peptide YY3-36; Peptide YY3-37; peptide-YY; prepro-PYY; PYY; PYY II; PYY1; PYY-1; PYY-2; PYYI; PYY-I; PYYII; PYY-II; RATGHYY; Yy
Gene Symbols Pyy
Host Species Chicken
Immunogen Synthetic peptide corresponding to amino acids 3-18 of human PYY.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 217212, 287730, 5697
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgY
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