Tocris™ R 7050

Inhibitor of TNF-alpha receptor 1 signaling

Manufacturer: Tocris™ 5432/50

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Catalog No. 54-325-0

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For Research Use Only


    Inhibitors R 7050
    Purity >98
    Molecular Weight 380.77
    Quantity 50mg
    Product Type R 7050

    Inhibitor of TNF-α receptor 1 (TNFR1) signaling; blocks TNFR1 association with TRADD and RIP1. Inhibits TNF-α-induced NF-κB and MAPK signaling pathway activation. Attenuates intracerebral hemorrhage-induced neurovascular injury in mice.

    • Chemical Name: 8-Chloro-4-(phenylthio)-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline
    • Formula: C16H8ClF3N4S
    • CAS Number: 303997-35-5
    • Solubility: Soluble to 20mM in DMSO
    • Purity: >98

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