R&D Systems KRIBB11, Tocris™

Heat shock factor (HSF) inhibitor

Manufacturer: R&D Systems 5480/10

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Catalog No. 548010

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Research Use Only. Not For Human or Veterinary Use


    Chemical Name or Material KRIBB11
    CAS 342639-96-7
    Assay Percent Range >99%
    Molecular Formula C13H12N6O2
    Formula Weight 284.27
    Synonym N2-1H-Indazol-5-yl-N6-methyl-3-nitro-2,6-pyridinediamine
    Recommended Storage Store at -20°C.
    Quantity 10mg
    Solubility Soluble to 100mM in DMSO
    Physical Form Solid
    Product Type Bioactive Small Molecules

    • Increases apoptosis in cancer cells treated with the HSP90 inhibitors Geldanamycin and 17-AAG
    • Blocks downstream induction of HSP27 and HSP70.
    • Inhibits tumor growth in vivo

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