RAD51C Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-156-3112	Bethyl Laboratories, Inc A302645AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt.

This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Specifications

• Antigen: RAD51C
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: DNA repair protein RAD51 homolog 3, RAD51 homolog C (S. cerevisiae), RAD51L2, Yeast RAD51 homolog 3
• Gene Symbols: RAD51C
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody

• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: O43502
• Gene ID (Entrez): 5889
• Immunogen: Between 326 and 376
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: RAD51C