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Rad6 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7140091
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50-155-7283 20 μL
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Catalog No. 50-155-7283 Supplier Bethyl Laboratories, Inc Supplier No. A300282AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predict

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at ′Lys-120′ to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes ′Lys-11′, as well as ′Lys-48′-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.

Specifications

Antigen Rad6
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene UBE2A
Gene Accession No. P49459
Gene Alias HHR6A, MRXS30, MRXSN, RAD6A, UBC2, HR6A, RAD6 homolog A, ubiquitin carrier protein A, ubiquitin-conjugating enzyme E2 A, ubiquitin-conjugating enzyme E2A (RAD6 homolog), ubiquitin-protein ligase A
Gene Symbols UBE2A
Host Species Rabbit
Immunogen Between 10 and 50
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7319
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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