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Rad6 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A300281A

Description
The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Rat, D. melanogaster, Bovine and Rabbit
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at ′Lys-120′ to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes ′Lys-11′, as well as ′Lys-48′-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.Specifications
Rad6 | |
Polyclonal | |
Unconjugated | |
UBE2A | |
HHR6A, MRXS30, MRXSN, RAD6A, UBC2, HR6A, RAD6 homolog A, ubiquitin carrier protein A, ubiquitin-conjugating enzyme E2 A, ubiquitin-conjugating enzyme E2A (RAD6 homolog), ubiquitin-protein ligase A | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
22209, 7319 | |
4° C | |
Liquid |
Immunohistochemistry, Western Blot | |
1 mg/ml | |
phosphate, tris citrate with 0.09% sodium azide; pH 7-8 | |
P49459, Q9Z255 | |
UBE2A | |
N-terminus | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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