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Rad6 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A300281A

Encompass_Preferred

Catalog No. 50-155-7278


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Rat, D. melanogaster, Bovine and Rabbit

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at ′Lys-120′ to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes ′Lys-11′, as well as ′Lys-48′-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
Specifications

Specifications

Rad6
Polyclonal
Unconjugated
UBE2A
HHR6A, MRXS30, MRXSN, RAD6A, UBC2, HR6A, RAD6 homolog A, ubiquitin carrier protein A, ubiquitin-conjugating enzyme E2 A, ubiquitin-conjugating enzyme E2A (RAD6 homolog), ubiquitin-protein ligase A
Rabbit
Antigen affinity chromatography
RUO
22209, 7319
4° C
Liquid
Immunohistochemistry, Western Blot
1 mg/ml
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
P49459, Q9Z255
UBE2A
N-terminus
100 μL
Primary
Human, Mouse
Antibody
IgG
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