Radixin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-9008	Proteintech Group Inc 137901AP150UL	150 μL

Description

Ezrin, radixin and moesin (ERM) proteins are widely distributed proteins located in the cellular cortex, in microvilli and adherens junctions. They are mediate linkage of actin cytoskeleton to plasma membrane in many cells. ERM proteins contain an N-terminal FERM (4.1/ezrin/radixin/moesin) domain that binds to phosphatidylinositol-(4, 5)phosphate and cellular membrane proteins. The ERM, particularly ezrin, is important for reconstructing cell-surface architecture during T cell activation. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. ERM activity is regulated in part by phosphorylation at a C-terminal threonine (ezrin-Thr567, radixin-Thr564, moesin-Thr558).

Specifications

• Antigen: Radixin
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P26043, P35241
• Gene ID (Entrez): 19684, 315655, 5962
• Immunogen: Radixin Fusion Protein Ag4813
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: RDX

• Concentration: 0.31 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: DFNB24, radixin, RDX
• Gene Symbols: Rdx
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody