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Invitrogen™ RASA1 Recombinant Rabbit Monoclonal Antibody (JE60-89)
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Catalog No. PIMA544868
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PIMA544868 100 μL
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Catalog No. PIMA544868 Supplier Invitrogen™ Supplier No. MA544868
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Description

Rabbit Recombinant Monoclonal Antibody

RASA1 Recombinant Monoclonal Antibody for Western Blot, IHC (P)

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASA1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JE60-89
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene RASA1
Gene Accession No. P20936
Gene Alias CMAVM; CM-AVM; Gap; GAPX; GTPase-activating protein; p120; p120 RAS GTPase activating protein; p120GAP; p120RASGAP; p120-rasGAP; PKWS; Ras GTPase-activating protein 1; ras GTPase-activating protein 1-like protein; Ras p21 protein activator; RAS p21 protein activator (GTPase activating protein RAS p21); RAS p21 protein activator (GTPase activating protein) 1; RAS p21 protein activator 1; Rasa; RASA1; RASGAP; triphosphatase-activating protein; unnamed protein product
Gene Symbols RASA1
Host Species Rabbit
Immunogen Synthetic peptide within human RASA1 250-300/1,047.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 218397, 5921
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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