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Rat anti-MHC Class II, Clone: M5/114.15.2, PE, Novus Biologicals™
SDP

Catalog No. NBP14376702 Shop All R&D Systems Products
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NBP14376702 0.2 mg
NBP14376705 0.05 mg
NBP14376701 0.1 mg
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Catalog No. NBP14376702 Supplier Novus Biologicals Supplier No. NBP1437670.2MG

Description

Rat Monoclonal Antibody

MHC class II (I-A/I-E) Monoclonal specifically detects MHC class II (I-A/I-E) in Human, Mouse samples. It is validated for Flow Cytometry.

Specifications

Antigen MHC Class II
Applications Flow Cytometry
Classification Monoclonal
Clone M5/114.15.2
Concentration 0.2 mg/mL
Conjugate PE
Dilution Flow Cytometry 1:10-1:1000
Formulation Aqueous buffer, may contain carrier protein/stabilizer (proprietary) with 0.09% Sodium Azide
Gene Alias class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM
Gene Symbols HLA-DMA
Host Species Rat
Immunogen The immunogen for this antibody was MHC Class II.
Purification Method Affinity Purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, Immune System Diseases, Immunology, Major Histocompatibility Complexes, Transcription Factors and Regulators
Primary or Secondary Primary
Gene ID (Entrez) 3108
Test Specificity The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.
Target Species Mouse
Content And Storage Store at 4C. Do not freeze.
Isotype IgG2b κ
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For Research Use Only

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