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RB1 Antibody (RB1/1754), DyLight 488, Novus Biologicals™
SDP

Catalog No. NBP254476G Shop All R&D Systems Products
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Catalog No. NBP254476G Supplier Novus Biologicals Supplier No. NBP254476G
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Description

Mouse Monoclonal Antibody

RB1 Monoclonal specifically detects RB1 in Human, Mouse samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen RB1
Applications Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone RB1/1754
Conjugate DyLight 488
Dilution Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein
Gene Symbols RB1
Host Species Mouse
Immunogen Recombinant human RB1 protein (Uniprot: P06400)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Cancer, Cell Cycle and Replication, Phospho Specific, Transcription Factors and Regulators, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 5925.0
Test Specificity Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
Target Species Human, Mouse
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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