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RBL2 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. p-7211926 Shop All Proteintech Group Inc Products
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50-173-5621 150 μL
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Catalog No. 50-173-5621 Supplier Proteintech Group Inc Supplier No. 272511AP150UL
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Description

Rabbit Polyclonal Antibody

Two retinoblastoma-related proteins, p107 and pRb2/p130 are structurally and functionally similar to the product of the retinoblastoma gene (pRb/p105). Like pRb they bind transforming proteins of DNA tumor viruses through a particular region called the "pocket domain". Both proteins play a fundamental role in growth control. The highest percentage of undetectable levels and the tightest inverse correlation with the histological grading and with PCNA expression in the most aggressive tumor types were found for pRb2/p130, which may suggest an important role for this protein in the pathogenesis and progression of lung cancer.

Specifications

Antigen RBL2
Applications Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene RBL2
Gene Accession No. Q08999
Gene Alias P130, pRb2, Rb2, RBL2, RBR 2, retinoblastoma like 2 (p130), Retinoblastoma like protein 2
Gene Symbols RBL2
Host Species Rabbit
Immunogen RBL2 Fusion Protein Ag25087
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5934
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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