RBM28 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-0978	Proteintech Group Inc 164841AP150UL	150 μL

Description

Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes. Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With VAPA, may regulate ER morphology. Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion. Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3. Also binds 25-hydroxycholesterol and cholesterol.

Specifications

• Antigen: RBM28
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q8CGC6, Q9NW13
• Gene ID (Entrez): 312182, 55131, 68272
• Immunogen: RBM28 Fusion Protein Ag9606
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: RBM28

• Concentration: 0.15 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: RBM28, RNA binding motif protein 28, RNA binding protein 28
• Gene Symbols: RBM28
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody