RBM28 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 164841AP
DescriptionPhosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes. Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With VAPA, may regulate ER morphology. Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion. Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3. Also binds 25-hydroxycholesterol and cholesterol.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|RBM28, RNA binding motif protein 28, RNA binding protein 28|
|312182, 55131, 68272|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|RBM28 Fusion Protein Ag9606|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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