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Invitrogen™ RCN3 Polyclonal Antibody
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Catalog No. PIPA5107237
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Quantity:
100 μL
Catalog No. Quantity
PIPA5107237 100 μL
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Catalog No. PIPA5107237

Supplier: Invitrogen™ PA5107237

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Description

Rabbit Polyclonal Antibody

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%.

Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed:16433634, PubMed:28939891). Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3. By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis. Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed:28939891). This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (PubMed:16433634). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen RCN3
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene RCN3
Gene Accession No. Q96D15
Gene Alias 6030455P07Rik; D530026G20Rik; D7Ertd671e; EF-hand calcium-binding protein RLP49; Rcn3; reticulocabin; reticulocalbin 3; reticulocalbin 3, EF-hand calcium binding domain; reticulocalbin-3; RLP49; UNQ239/PRO272
Gene Symbols RCN3
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal region of Human RCN3.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57333
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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