R&D Systems™ Recombinant Human BACE-2 Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Enzyme Activity

Measured by its ability to cleave a fluorogenic peptide substrate Mca-KPLGL-Dpa-AR-NH2 (Catalog # ES010 ). The specific activity is >70 pmol/min/μg, as measured under the described conditions.

Specifications

• Host Species: Human
• Purity: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Storage Buffer: Supplied as a 0.2 μm filtered solution in Tris and NaCl.
• Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20°C to -70°C as supplied. 3 months, -20°C to -70°C under sterile conditions after opening.
• Accession Number: Q9Y5Z0-1
• Gene ID (Entrez): 25825
• Gene Alias: AEPLC, Asp 1, ASP1, ASP21, Aspartic-like protease 56 kDa, Aspartyl protease 1, BACE2, beta secretase 2, beta-secretase 2, beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, Beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, beta-site APP-cleaving enzyme 2, beta-site APP-cleaving enzyme 2, EC 3.4.2310 ALP5656 kDa aspartic-like protease, CEAP1, Down region aspartic protease, Down syndrome region aspartic protease, DRAPBAE2, EC 3.4.23, EC 3.4.23.45, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, transmembrane aspartic proteinase Asp1
• Conjugate: Unconjugated
• Source: Mouse myeloma cell line,NS0-derived human BACE-2 protein Phe29-Pro466,with a C-terminal 10-His tag
• Quantity: 20 μg
• Molecular Weight (g/mol): M.W. (Observed): 48-60 kDa, reducing conditions