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Retinol Binding Protein RBP Antibody (SPM442), Alexa Fluor™ 647, Novus Biologicals™
SDP

Catalog No. NBP234410Y Shop All R&D Systems Products
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NBP234410Y 0.1 mL
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Catalog No. NBP234410Y Supplier Novus Biologicals Supplier No. NBP234410AF647
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Description

Mouse Monoclonal Antibody

Retinol Binding Protein RBP Monoclonal specifically detects Retinol Binding Protein RBP in Human, Mouse, Rat, Goat, Monkey, Rabbit samples. It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen RBP4/Retinol-Binding Protein 4
Applications Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone SPM442
Conjugate Alexa Fluor 647
Dilution Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias interstitial, Plasma retinol-binding protein, retinol binding protein 4, plasma, retinol-binding protein 4, plasma
Gene Symbols RBP4
Host Species Mouse
Immunogen Retinol binding protein purified from human plasma
Molecular Weight of Antigen 23 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer, Diabetes Research, Lipid and Metabolism
Primary or Secondary Primary
Gene ID (Entrez) 5950
Test Specificity Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This monoclonal antibody recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.
Target Species Human, Mouse, Rat, Goat, Primate, Rabbit
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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