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RHOB Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$395.30

Specifications

Antigen RHOB
Concentration 0.2 mg/mL
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-172-9367
SDP
Encompass_Preferred
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Proteintech Group Inc
143261AP150UL
150 μL
Each of 1 for $395.30
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Description

Description

RhoB (Rho-related GTP-binding protein) mediates apoptosis in neoplastically transformed cells after DNA damage. While not essential for development, it does affect cell adhesion and growth factor signaling in transformed cells. RhoB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a tumor supressor - deletion of RhoB causes tumor formation.
Specifications

Specifications

RHOB
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
Rabbit
Human, Mouse
IgG
-20°C
0.2 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications
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