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RNase T2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501728984 Shop All Proteintech Group Inc Products
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50-172-8984 150 μL
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Catalog No. 50-172-8984 Supplier Proteintech Group Inc Supplier No. 137531AP150UL
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Rabbit Polyclonal Antibody

RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human maligcies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.

Specifications

Antigen RNase T2
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RNASET2
Gene Accession No. C0HKG5, O00584
Gene Alias Ribonuclease 6, Ribonuclease T2, RNASE6PL, RNASET2
Gene Symbols RNASET2, Rnaset2a
Host Species Rabbit
Immunogen RNase T2 Fusion Protein Ag4695
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100037283, 8635
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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