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  5. Tocris Bioscience™ Ro 6842262, >98%

Tocris Bioscience™ Ro 6842262, >98%
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Catalog No. 591310
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59-131-0 10 mg
59-135-0 50 mg
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Catalog No. 59-131-0 Supplier Tocris Bioscience™ Supplier No. 5913/10
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Description

Potent LPA1 antagonist

Potent LPA1 antagonist (IC50 = 25 nM). Exhibits >1,200-fold selectivity for LPA1 over LPA3. Attenuates NHLF human lung fibroblast cell proliferation and contraction in vitro. Also reduces plasma histamine levels in mouse LPA-challenge model. Orally bioavailable.

Chemical Identifiers

CAS 1396006-71-5
Molecular Formula C28H26N4O4

Specifications

Quantity 10 mg
Solubility Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight 482.53
Purity >98%
Molecular Weight (g/mol) 482.54
Chemical Name or Material 1-[4'-[4-Methyl-5-[[[(1R)-1-phenylethoxy]carbonylamino]-1H-1,2,3-triazol-1-yl][1,1'-biph

Safety and Handling

Recommended Storage Store at -20°C
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