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ROC1 Ab-1 Rabbit Polyclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ ROC1 Ab-1, Rabbit Polyclonal Antibody.
Supplier: Epredia RB069P
Description
ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex(APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.Host Species: Rabbit
Isotype: IgG
Species Reactivity: Human and Mouse. Others not known.
Epitope: aa 97-108
Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
Molecular Weight: 13kDa
Positive Control: HeLa cells
Cellular Localization: Nuclear
Recommended for:
- Western Blotting
- Immunoprecipitation (Native verified)
Note:
USA: RUO; Int'l: RUO
Specifications
ROC1 Ab-1 | |
Polyclonal | |
1mg/mL | |
Rabbit | |
Purified with BSA and azide | |
RUO | |
Primary | |
Concentrated |
Western Blot | |
Polyclonal | |
Unconjugated | |
A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1 | |
1 mL | |
Cell Cycle | |
Human | |
IgG |
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