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ROC1 Ab-1 Rabbit Polyclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ ROC1 Ab-1, Rabbit Polyclonal Antibody.
Specifications
| Antigen | ROC1 Ab-1 |
|---|---|
| Concentration | 1mg/mL |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Form | Purification Method | Quantity | Price | Quantity & Availability | |||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Form | Purification Method | Quantity | Price | Quantity & Availability | |||
|
RB069P0
|
Epredia
RB069P0 |
Concentrated | Purified with BSA and azide | 100 μL | N/A | N/A | N/A | ||
|
RB069P1
|
Epredia
RB069P1 |
Concentrated | Purified with BSA and azide | 500 μL | N/A | N/A | N/A | ||
|
RB069P
|
Epredia
RB069P |
Concentrated | Purified with BSA and azide | 1 mL | N/A | N/A | N/A | ||
|
RB069P1ABX
|
Epredia
RB069P1ABX |
Concentrated | Purified without BSA and azide | 500 μL | N/A | N/A | N/A | ||
|
RB069PABX
|
Epredia
RB069PABX |
Concentrated | Purified without BSA and azide | 1 mL | N/A | N/A | N/A | ||
Description
ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex(APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.Host Species: Rabbit
Isotype: IgG
Species Reactivity: Human and Mouse. Others not known.
Epitope: aa 97-108
Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
Molecular Weight: 13kDa
Positive Control: HeLa cells
Cellular Localization: Nuclear
Recommended for:
- Western Blotting
- Immunoprecipitation (Native verified)
1. Tan P, et al. Mol Cell 1999 Apr 3 (4): 527.
2. Skowyra D, et al. Science 1999. 284 (5414): 662.
3. Ohta T, et al. Mol Cell 1999 Apr 3(4): 535.
Specifications
| ROC1 Ab-1 | |
| Western Blot | |
| Unconjugated | |
| Rabbit | |
| Cell Cycle | |
| A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1 | |
| Primary |
| 1mg/mL | |
| Polyclonal | |
| Concentrated | |
| RUO | |
| Human | |
| IgG |
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