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ROCK1 Antibody (154C1465), Janelia Fluor™ 646 - (active/cleaved), Novus Biologicals™
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Catalog No. N233238J646 Shop All R&D Systems Products
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N233238J646 0.1 mL
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Catalog No. N233238J646 Supplier Novus Biologicals Supplier No. NBP233238JF646
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Description

Mouse Monoclonal Antibody

ROCK1 Monoclonal specifically detects ROCK1 in Human, Mouse, Rat, Canine, Primate, Rabbit samples. It is validated for Western Blot, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen ROCK1
Applications Western Blot, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone 154C1465
Conjugate Janelia Fluor 646
Dilution Western Blot, Immunocytochemistry/Immunofluorescence
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1
Gene Symbols ROCK1
Host Species Mouse
Immunogen This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to amino acids 1114-1126 GNLPESRIEGWLS of human ROCK-1. This sequence is 100% conserved between human, chimpanzee, mouse, rat, dog, and rabbit. This immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1.
Purification Method Protein G purified
Quantity 0.1 mL
Research Discipline Apoptosis, Breast Cancer, Cancer, Signal Transduction, Wnt Signaling Pathway
Primary or Secondary Primary
Gene ID (Entrez) 6093.0
Test Specificity This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.
Target Species Human, Mouse, Rat, Canine, Primate, Rabbit
Content And Storage Store at 4°C in the dark.
Isotype IgG
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