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Tocris Bioscience™ RWJ 67657
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Catalog No. 299910
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Catalog No. Quantity
29-991-0 10 mg
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Description

Potent, selective p38α and p38β inhibitor

Selective p38α and p38β inhibitor (IC50 values are 1 and 11 μM respectively) that displays no activity at p38γ, p38δ and a range of other kinases. Potently inhibits TNF-α and IL-1β release (IC50 values are 3 and 11 nM respectively) and suppresses HIV-1 replication in T cells in vitro. Displays cardioprotective and anti-inflammatory activity in vivo. Orally active.

Chemical Identifiers

CAS 215303-72-3
Molecular Formula C27H24FN3O

Specifications

Quantity 10 mg
Formula Weight 425.5
Purity >98%
Molecular Weight (g/mol) 425.507
Chemical Name or Material RWJ 67657

Safety and Handling

Recommended Storage Store at Room Temperature
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