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  5. Tocris Bioscience™ Ryuvidine

Tocris Bioscience™ Ryuvidine
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Catalog No. p-4784466
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

SETD8 inhibitor; also CDK4 inhibitor

Inhibitor of SETD8 protein lysine methyltransferase (PKMT) (IC50 = 0.5 μM); suppresses H4K20 monomethylation in vitro. Also inhibits cyclin-dependent kinase (CDK) 4 (IC50 = 6.0 μM at CDK4/cyclin D1). Induces S phase accumulation in HEK293T cells. Cytotoxic against a range of human cancer cells.

Chemical Identifiers

CAS 265312-55-8
Molecular Formula C15H12N2O2S

Specifications

Quantity 10 mg
Formula Weight 284.33
Purity >98%
Molecular Weight (g/mol) 284.333
Chemical Name or Material Ryuvidine

Safety and Handling

Recommended Storage Store at +4°C
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