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S100B Antibody (4C4.9), DyLight 594, Novus Biologicals™
SDP

Catalog No. NB029893 Shop All R&D Systems Products
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NB029893 0.1 mL
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Catalog No. NB029893 Supplier Novus Biologicals Supplier No. NBP233168DL594
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Description

Mouse Monoclonal Antibody

S100B Monoclonal specifically detects S100B in Human, Mouse, Rat, Bovine samples. It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen S100A1
Applications Western Blot, ELISA, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 4C4.9
Conjugate DyLight 594
Dilution Western Blot, ELISA, Immunohistochemistry-Paraffin
Formulation 50mM Sodium Borate
Gene Alias protein S100-A1, S100 alpha, S100 calcium binding protein A1, S100 calcium-binding protein A1S100, S-100 protein alpha chain, S-100 protein subunit alpha, S100 protein, alpha polypeptide, S100A, S100-alpha
Host Species Mouse
Immunogen Purified bovine brain S100B protein (Uniprot: P04271)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Alzheimers Research, Apoptosis, Biologically Active Proteins, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Epigenetics, Hypoxia, Lipid and Metabolism, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Peroxisome Markers, Signal Transduction, Stem Cells
Primary or Secondary Primary
Gene ID (Entrez) 6271
Test Specificity S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
Target Species Human, Mouse, Rat, Bovine
Content And Storage Store at 4°C in the dark.
Form Purified
Isotype IgG2a κ
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