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S1PR2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen S1PR2
Concentration 0.21 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-558-779
SDP
Encompass_Preferred
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Proteintech Group Inc
211801AP150UL
150 μL
Each of 1 for $518.60
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Description

Description

The EDG (endothelial differentiation gene) family of G protein coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high-affinity. EDG-6 is a low-affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain. Expressed in lymphoid and hematopoietic tissues and in lung, EDG-6 signals through Gi/o proteins, which activate growth related pathways.
Specifications

Specifications

S1PR2
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
Rabbit
Human, Mouse, Rat
O95136, P47752, P52592
14739, 29415, 9294
S1PR2 Fusion Protein Ag15470
Primary
-20°C
S1PR2
0.21 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
AGR16, EDG 5, EDG5, Gpcr13, H218, LPB2, S1P receptor 2, S1P receptor Edg 5, S1P2, S1PR2
S1PR2
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
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Documents

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