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  5. Tocris Bioscience™ SAK 3

Tocris Bioscience™ SAK 3
GREENER_CHOICE

Catalog No. p-7146023
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent CaV3.1/3.3 activator; orally bioavailable

SAK 3 is a potent CaV3.1 and CaV3.3 activator. Enhances CaV3.1 and CaV3.3, but not CaV3.2 activity at concentrations of 0.01 - 10 M in neuro2A cells in vitro. Elevates ACh levels in hippocampus. Rescues impaired memory-related behaviors, promotes adult neurogenesis and displays antidepressant-like effects in OBX mice. Orally bioavailable.

Specifications

Chemical Name or Material Ethyl 8′-methyl-2′,4-dioxo-2-(piperidin-1-yl)-2′H-spiro[cyclopent[2]ene-1,3′-imidazo[1,2-a]pyridine]-3-carboxylate
CAS 1256269-87-0
Quantity 5 mg
Target Cav3.x Channel Activators
Molecular Formula C20H23N3O4
Purity 98%
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