Invitrogen™ SARS-CoV-2 Membrane Recombinant Rabbit Monoclonal Antibody (HL1087)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA546923

Catalog No. PIMA546923

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

The coronavirus membrane protein (M) is the most abundant viral structural protein and plays a central role in virus assembly and morphogenesis M protein forms a mushroom-shaped dimer, composed of two transmembrane domain-swapped three-helix bundles and two intravirion domains M protein further assembles into higher-order oligomers A highly conserved hinge region is key for conformational changes The M protein dimer is unexpectedly similar to SARS-CoV-2 ORF3a, a viral ion channel The interaction analyses of M protein with nucleocapsid protein (N) and RNA suggest that the M protein mediates the concerted recruitment of these components through the positively charged intravirion domain [PMID: 35931673].

Specifications

• Antigen: SARS-CoV-2 Membrane
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Clone: HL1087
• Conjugate: Unconjugated
• Gene Alias: CoV-2; SARS
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of SARS-CoV-2 (COVID-19) Membrane. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid