SARS-CoV-2 Spike Antibody (CR3022), Alexa Fluor™ 750 - Chimeric, Novus Biologicals™

Rabbit Monoclonal Antibody

Supplier:  Novus Biologicals NBP290979AF750

Catalog No. NB025753

Description

SARS-CoV-2 Spike Monoclonal antibody specifically detects SARS-CoV-2 Spike in SARS-CoV-2, SARS-CoV samples. It is validated for ELISA, Immunocytochemistry, Immunofluorescence.

Specifications

• Antigen: SARS-CoV-2 Spike
• Classification: Monoclonal
• Conjugate: Alexa Fluor 750
• Gene Alias: 2019-nCoV S Protein, 2019-nCoV Spike, COVID-19 Spike, Human coronavirus spike glycoprotein, SARS-CoV-2, SARS-COV-2 S protein, SARS-COV-2 Spike glycoprotein, SARSCOV2 Spike protein, Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein, Spike glycoprotein
• Host Species: Rabbit
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Test Specificity: This antibody binds to both SARS-CoV and SARS-CoV-2 with high affinity (PMID: 16796401 & 32065055). It binds the amino acids 318-510 in the S1 domain of the SARS-CoV Spike protein as well as SARS-CoV-2 (COVID-19) Spike protein. The antibody also binds to P462L-substituted S318-510 fragments of the SARS spike protein. The binding epitope is only accessible in the "open" confromation of the spike protein (Joyce et al. 2020). NBP2-90979 cross-reacts with spike protein of Omicron and Delta variants.
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG κ

• Applications: ELISA
• Clone: CR3022
• Formulation: 50mM Sodium Borate
• Gene Symbols: S
• Immunogen: The original monoclonal antibody was generated by sequencing peripheral blood lymphocytes of a patient exposed to the SARS-CoV.
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Target Species: SARS-CoV
• Form: Purified