Invitrogen™ SARS-CoV-2 Spike Protein S2/S2' (strain Wuhan-Hu-1) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143458

Catalog No. PIPA5143458

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor to gain entry into a cell to initiate infection SARS-2-S is cleaved into S1 and S2 subunits, with S1 serving the function of receptor-binding and S2 serving the function of membrane fusion The S protein undergoes two crucial cleavage events, with the first splitting S1 and S2 and the second splitting S2 into FP and S2' [PMID: 33466921].

Specifications

• Antigen: SARS-CoV-2 Spike Protein S2/S2' (strain Wuhan-Hu-1)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: 2019-nCoV Spike; COVID-19 Spike; SARS-CoV-2 Spike
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of SARS-CoV-2 Spike (S2). (SARS-CoV-2 (strain Wuhan-Hu-1)). The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% Proclin 300; pH 7
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG