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SART1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7140866
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Catalog No. Quantity
50-156-0352 20 μL
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Catalog No. 50-156-0352 Supplier Bethyl Laboratories, Inc Supplier No. A301423AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

This gene encodes two proteins, the SART1protein expressed in the nucleus of the majority of proliferating cells, and the SART1protein expressed in the cytosol of epithelial cancers. The SART1protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

Specifications

Antigen SART1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene SART1
Gene Accession No. O43290
Gene Alias SART1; squamous cell carcinoma antigen recognised by T cells; ARA1; Ara1; HOMS1; MGC2038; SART1259; Snu66; IgE autoantigen; SART1(259) protein; SART1(800) protein; U4/U6.U5 tri-snRNP-associated 110 kDa protein; squamous cell carcinoma antigen recognised by T cells; squamous cell carcinoma antigen recognized by T cells 1; SNRNP110; small nuclear ribonucleoprotein 110kDa (U4/U6.U5)
Gene Symbols SART1
Host Species Rabbit
Immunogen Between 750 and 800
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9092
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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