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Tocris Bioscience™ SB 271046 hydrochloride
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Catalog No. 336850
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Catalog No. Quantity
33-685-0 50 mg
33-681-0 10 mg
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Catalog No. 33-685-0 Supplier Tocris Bioscience™ Supplier No. 3368/50
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Description

Selective, orally active 5-HT6 antagonist

Selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.55, 6.35, 6.27, 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and < 4.99 at 5-HT6, 5-HT1D, 5-HT1A, D3, 5-HT1B, 5-HT1F, α1B, 5-HT2C, 5-HT2A, D2, 5-HT2B, 5-HT7, 5-HT4 and 5-HT1E respectively) and is > 200-fold selective over 55 other receptors, enzymes and ion channels. Increases extracellular glutamate and aspartate in the frontal cortex, and exhibits anticonvulsant activity (EC50 = 0.16 μM).

Chemical Identifiers

CAS 209481-20-9
Molecular Formula C20H23Cl2N3O3S2

Specifications

Quantity 50 mg
Formula Weight 488.45
Purity >99%
Molecular Weight (g/mol) 488.442
Chemical Name or Material SB 271046 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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