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  5. Tocris Bioscience™ SB 297006

Tocris Bioscience™ SB 297006
GREENER_CHOICE

Catalog No. 421310
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective CCR3 antagonist

SB 297006 is a potent and selective CCR3 antagonist (IC50 = 39 nM). Displays 250-fold selectivity for CCR3 over other chemokine receptors, including CXCR1, CXCR2, CCR1 and CCR7 (IC50 >27 μM). Inhibits calcium mobilization induced by MCP-4, eotaxin-2 and eotaxin in RBL-2H3 cells transfected with CCR3 (IC50 values are 80, 90 and 210 nM respectively).

Specifications

Quantity 10 mg
Product Type SB 297006
Purity >99%
Molecular Weight (g/mol) 342.35
Inhibitors SB 297006

For Research Use Only

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