Tocris™ SB 297006

Potent and selective CCR3 antagonist

Manufacturer: Tocris™ 4213/10

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Catalog No. 42-131-0

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Disclaimers:

For Research Use Only


    Specifications

    Product Type SB 297006
    Inhibitors SB 297006
    Purity >99
    Molecular Weight 342.35
    Quantity 10mg

    Potent and selective CCR3 antagonist (IC50 = 39nM). Displays 250-fold selectivity for CCR3 over other chemokine receptors, including CXCR1, CXCR2, CCR1 and CCR7 (IC50 >27µM). Inhibits calcium mobilization induced by MCP-4, eotaxin-2 and eotaxin in RBL-2H3 cells transfected with CCR3 (IC50 values are 80, 90 and 210nM respectively).

    • Chemical Name: N-Benzoyl-4-nitroaniline ethyl ester
    • Formula: C18H18N2O5
    • CAS Number: 58816-69-6
    • Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
    • Purity: >99

  • Description & Specifications

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