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Tocris Bioscience™ SB 657510

Selective urotensin-II (UT) receptor antagonist

Supplier:  Tocris Bioscience™ 3571/50

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Catalog No. 35-715-0R

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Description

Description

Selective urotensin-II (UT) receptor antagonist (K i values are 61, 17, 30, 65 and 56 nM at human, monkey, cat, rat and mouse receptors respectively). Inhibits U-II-induced intracellular Ca 2+ mobilization (IC 50 = 180 nM) and antagonizes the contractile action of U-II in isolated mammalian arteries and aortae (EC 50 = 50 - 189 nM).
Specifications

Specifications

>98%
SB 657510
SB 657510
50 mg
505.81
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