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Tocris Bioscience™ SB 747651A dihydrochloride
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Catalog No. 463010
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10 mg
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Catalog No. Quantity
46-301-0 10 mg
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Catalog No. 46-301-0 Supplier Tocris Bioscience™ Supplier No. 4630/10
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Description

Potent MSK1 inhibitor; also inhibits other AGC group kinases

Potent, ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor (IC50 = 11 nM in an in vitro kinase assay); targets the N-terminal kinase domain. Inhibits MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells. Blocks IL-10 production in macrophages.

Chemical Identifiers

CAS 1781882-72-1
Molecular Formula C16H24Cl2N8O

Specifications

Quantity 10 mg
Formula Weight 415.32
Purity >98%
Molecular Weight (g/mol) 415.323
Chemical Name or Material SB 747651A dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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