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  6. SB 772077B dihydrochloride, Tocris Bioscience™

SB 772077B dihydrochloride, Tocris Bioscience™
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Catalog No. 411850
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent Rho-kinase inhibitor; vasodilator

SB 772077B dihydrochloride is a potent Rho-kinase (ROCK) inhibitor (IC50 value of approximately 5.6 nM at recombinant human ROCK1 and 2). Decreases pulmonary and systemic arterial blood pressures and increases cardiac output. Exhibits vasodilator activity that is more potent than Y-27632 (Cat. No 1254) or Fasudil (Cat. No. 0541).

Chemical Identifiers

CAS 607373-46-6
Molecular Formula C15H20Cl2N8O2
Molecular Weight (g/mol) 415.279
InChI Key HSROPTGRSYJPJY-JZGIKJSDSA-N
Synonym sb 772077b dihydrochloride, 3s-1-2-4-amino-1,2,5-oxadiazol-3-yl-1-ethyl-1h-imidazo 4,5-c pyridin-7-yl carbonyl-3-pyrrolidinamine dihydrochloride
PubChem CID 69157798
IUPAC Name [2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanone;dihydrochloride
SMILES CCN1C2=C(C=NC=C2C(=O)N3CCC(C3)N)N=C1C4=NON=C4N.Cl.Cl

Specifications

Quantity 50 mg
Formula Weight 415.28
Percent Purity >99%
Chemical Name or Material SB 772077B dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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